C375-0123 Screening compound: (4-BENZYLPIPERAZINO)[1-(8-QUINOLYLSULFONYL)-4-PIPERIDYL]METHANONE

C375-0123 Screening compound: (4-BENZYLPIPERAZINO)[1-(8-QUINOLYLSULFONYL)-4-PIPERIDYL]METHANONE
C375-0123 Screening compound: (4-BENZYLPIPERAZINO)[1-(8-QUINOLYLSULFONYL)-4-PIPERIDYL]METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound C375-0123
(4-BENZYLPIPERAZINO)[1-(8-QUINOLYLSULFONYL)-4-PIPERIDYL]METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C375-0123

Molecular Formula

C26H30N4O3S (C26 H30 N4 O3 S)

Compound Name

(4-BENZYLPIPERAZINO)[1-(8-QUINOLYLSULFONYL)-4-PIPERIDYL]METHANONE

IUPAC name

n/a

SMILES

O=C(C(CC1)CCN1S(c1cccc2cccnc12)(=O)=O)N1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C26H30N4O3S/c31-26(29-18-16-28(17-19-29)20-21-6-2-1-3-7-21)23-11-14-30(15-12-23)34(32,33)24-10-4-8-22-9-5-13-27-25(22)24/h1-10,13,23H,11-12,14-20H2

InChI Key

KYFJWKKTVJQUPL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14754582

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.62

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.389

Distribution Coefficient, logD

2.337

Water Solubility, LogSw

-2.48

Polar Surface Area

61.671

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

6.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

C375-0123 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Dark Chemical Matter Library (18430 compounds)

GPCR Targeted Library (31838 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Structure:
  • Pool
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C375-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C375-0123?
Check Price and Availability of C375-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C375-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C375-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C375-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C375-0123 available by request