C535-1000 Screening compound: 1-{1-[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole

C535-1000 Screening compound: 1-{1-[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole
C535-1000 Screening compound: 1-{1-[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound C535-1000
1-{1-[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C535-1000

Molecular Formula

C28H28ClN5O (C28 H28 ClN5 O)

Compound Name

1-{1-[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole

IUPAC name

1-{1-[3-(4-chlorophenyl)-25-dimethylpyrazolo[15-a]pyrimidin-7-yl]piperidine-4-carbonyl}-23-dihydro-1H-indole

SMILES

Cc1nn2c(N(CC3)CCC3C(N(CC3)c4c3cccc4)=O)cc(C)nc2c1-c(cc1)ccc1Cl

InChI

InChI=1S/C28H28ClN5O/c1-18-17-25(34-27(30-18)26(19(2)31-34)21-7-9-23(29)10-8-21)32-14-11-22(12-15-32)28(35)33-16-13-20-5-3-4-6-24(20)33/h3-10,17,22H,11-16H2,1-2H3

InChI Key

DENRSOAOWBNWGF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14768673

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.02

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.480

Distribution Coefficient, logD

3.974

Water Solubility, LogSw

-5.98

Polar Surface Area

38.536

Acid Dissociation Constant (pKa)

21.39

Base Dissociation Constant (pKb)

8.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

C535-1000 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C535-1000 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C535-1000?
Check Price and Availability of C535-1000, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C535-1000 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C535-1000
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C535-1000
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C535-1000 available by request