C614-0186 Screening compound: 2-[4-(4-fluorophenyl)piperazin-1-yl]-4-methylquinolin-7-ol

C614-0186 Screening compound: 2-[4-(4-fluorophenyl)piperazin-1-yl]-4-methylquinolin-7-ol
C614-0186 Screening compound: 2-[4-(4-fluorophenyl)piperazin-1-yl]-4-methylquinolin-7-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound C614-0186
2-[4-(4-fluorophenyl)piperazin-1-yl]-4-methylquinolin-7-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C614-0186

Molecular Formula

C20H20FN3O (C20 H20 FN3 O)

Compound Name

2-[4-(4-fluorophenyl)piperazin-1-yl]-4-methylquinolin-7-ol

IUPAC name

2-[4-(4-fluorophenyl)piperazin-1-yl]-4-methylquinolin-7-ol

SMILES

Cc1cc(N(CC2)CCN2c(cc2)ccc2F)nc2cc(O)ccc12

InChI

InChI=1S/C20H20FN3O/c1-14-12-20(22-19-13-17(25)6-7-18(14)19)24-10-8-23(9-11-24)16-4-2-15(21)3-5-16/h2-7,12-13,25H,8-11H2,1H3

InChI Key

JXDTUVCWVHPEIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14776085

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

337.4

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.946

Distribution Coefficient, logD

4.942

Water Solubility, LogSw

-4.64

Polar Surface Area

32.362

Acid Dissociation Constant (pKa)

9.72

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

C614-0186 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

STING Agonist Library (5895 compounds)

SmartTM Library (51161 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Immune system
  • Nervous system
Targets:
  • Others
  • Ion Channels

References: we are preparing a list of scientific research reports with C614-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C614-0186?
Check Price and Availability of C614-0186, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C614-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C614-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C614-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C614-0186 available by request