C614-0188 Screening compound: 2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methylquinolin-7-ol

C614-0188 Screening compound: 2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methylquinolin-7-ol
C614-0188 Screening compound: 2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methylquinolin-7-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound C614-0188
2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methylquinolin-7-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C614-0188

Molecular Formula

C21H23N3O2 (C21 H23 N3 O2)

Compound Name

2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methylquinolin-7-ol

IUPAC name

2-[4-(4-methoxyphenyl)piperazin-1-yl]-4-methylquinolin-7-ol

SMILES

Cc1cc(N(CC2)CCN2c(cc2)ccc2OC)nc2cc(O)ccc12

InChI

InChI=1S/C21H23N3O2/c1-15-13-21(22-20-14-17(25)5-8-19(15)20)24-11-9-23(10-12-24)16-3-6-18(26-2)7-4-16/h3-8,13-14,25H,9-12H2,1-2H3

InChI Key

KKKQJQHYCBKAGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14776086

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

349.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.899

Distribution Coefficient, logD

4.895

Water Solubility, LogSw

-4.62

Polar Surface Area

39.906

Acid Dissociation Constant (pKa)

9.72

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

C614-0188 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Receptors Annotated Library (5376 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

STING Agonist Library (5895 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with C614-0188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C614-0188?
Check Price and Availability of C614-0188, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C614-0188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C614-0188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C614-0188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C614-0188 available by request