C619-0559 Screening compound: (2E)-3-(furan-2-yl)-N-{9-[(2-methoxyphenyl)amino]-5,6,7,8-tetrahydroacridin-2-yl}prop-2-enamide

C619-0559 Screening compound: (2E)-3-(furan-2-yl)-N-{9-[(2-methoxyphenyl)amino]-5,6,7,8-tetrahydroacridin-2-yl}prop-2-enamide
C619-0559 Screening compound: (2E)-3-(furan-2-yl)-N-{9-[(2-methoxyphenyl)amino]-5,6,7,8-tetrahydroacridin-2-yl}prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C619-0559
(2E)-3-(furan-2-yl)-N-{9-[(2-methoxyphenyl)amino]-5,6,7,8-tetrahydroacridin-2-yl}prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C619-0559

Molecular Formula

C27H25N3O3 (C27 H25 N3 O3)

Compound Name

(2E)-3-(furan-2-yl)-N-{9-[(2-methoxyphenyl)amino]-5,6,7,8-tetrahydroacridin-2-yl}prop-2-enamide

IUPAC name

(2E)-3-(furan-2-yl)-N-{9-[(2-methoxyphenyl)amino]-5678-tetrahydroacridin-2-yl}prop-2-enamide

SMILES

COc(cccc1)c1Nc1c(cc(cc2)NC(/C=C/c3ccco3)=O)c2nc2c1CCCC2

InChI

InChI=1S/C27H25N3O3/c1-32-25-11-5-4-10-24(25)30-27-20-8-2-3-9-22(20)29-23-14-12-18(17-21(23)27)28-26(31)15-13-19-7-6-16-33-19/h4-7,10-17H,2-3,8-9H2,1H3,(H,28,31)(H,29,30)

InChI Key

IIXGLNYPBOPIOC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14777633

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.941

Distribution Coefficient, logD

4.926

Water Solubility, LogSw

-5.54

Polar Surface Area

55.067

Acid Dissociation Constant (pKa)

12.17

Base Dissociation Constant (pKb)

8.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

C619-0559 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

MCL1 Targeted Library (12200 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with C619-0559 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C619-0559?
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What is the minimum amount of C619-0559 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C619-0559
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C619-0559
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C619-0559 available by request