C637-0278 Screening compound: 4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-phenylpiperazine-1-carbothioamide

C637-0278 Screening compound: 4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-phenylpiperazine-1-carbothioamide
C637-0278 Screening compound: 4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-phenylpiperazine-1-carbothioamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C637-0278
4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-phenylpiperazine-1-carbothioamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C637-0278

Molecular Formula

C19H24N6OS (C19 H24 N6 OS)

Compound Name

4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-phenylpiperazine-1-carbothioamide

IUPAC name

4-[6-(morpholin-4-yl)pyridazin-3-yl]-N-phenylpiperazine-1-carbothioamide

SMILES

S=C(Nc1ccccc1)N(CC1)CCN1c(cc1)nnc1N1CCOCC1

InChI

InChI=1S/C19H24N6OS/c27-19(20-16-4-2-1-3-5-16)25-10-8-23(9-11-25)17-6-7-18(22-21-17)24-12-14-26-15-13-24/h1-7H,8-15H2,(H,20,27)

InChI Key

FKNYGCQAIMTBIN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14778587

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.797

Distribution Coefficient, logD

2.792

Water Solubility, LogSw

-3.14

Polar Surface Area

46.428

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

7.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

C637-0278 in Drug Discovery

Included in Screening Libraries

Dark Chemical Matter Library (18430 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Covalent Inhibitors Library (7986 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
  • Cyclic compounds
  • 3D
  • Fragments
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with C637-0278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C637-0278?
Check Price and Availability of C637-0278, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C637-0278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C637-0278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C637-0278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C637-0278 available by request