C648-0373 Screening compound: N-(2,4-dimethoxyphenyl)-3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)propanamide

C648-0373 Screening compound: N-(2,4-dimethoxyphenyl)-3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)propanamide
C648-0373 Screening compound: N-(2,4-dimethoxyphenyl)-3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C648-0373
N-(2,4-dimethoxyphenyl)-3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C648-0373

Molecular Formula

C21H24N4O7S (C21 H24 N4 O7 S)

Compound Name

N-(2,4-dimethoxyphenyl)-3-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamido)propanamide

IUPAC name

N-(24-dimethoxyphenyl)-3-(13-dimethyl-24-dioxo-1234-tetrahydroquinazoline-6-sulfonamido)propanamide

SMILES

CN(c(ccc(S(NCCC(Nc(ccc(OC)c1)c1OC)=O)(=O)=O)c1)c1C(N1C)=O)C1=O

InChI

InChI=1S/C21H24N4O7S/c1-24-17-8-6-14(12-15(17)20(27)25(2)21(24)28)33(29,30)22-10-9-19(26)23-16-7-5-13(31-3)11-18(16)32-4/h5-8,11-12,22H,9-10H2,1-4H3,(H,23,26)

InChI Key

SXYHKXOJHXJBKY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14779253

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.51

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

1.492

Distribution Coefficient, logD

1.492

Water Solubility, LogSw

-2.65

Polar Surface Area

110.567

Acid Dissociation Constant (pKa)

10.13

Base Dissociation Constant (pKb)

2.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

C648-0373 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with C648-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C648-0373?
Check Price and Availability of C648-0373, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C648-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C648-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C648-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C648-0373 available by request