C883-0381 Screening compound: N-[2-(4-chlorophenyl)ethyl]-3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide

C883-0381 Screening compound: N-[2-(4-chlorophenyl)ethyl]-3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide
C883-0381 Screening compound: N-[2-(4-chlorophenyl)ethyl]-3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C883-0381
N-[2-(4-chlorophenyl)ethyl]-3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C883-0381

Molecular Formula

C23H21ClN4O (C23 H21 ClN4 O)

Compound Name

N-[2-(4-chlorophenyl)ethyl]-3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide

SMILES

Cc(c(C(NCCc(cc1)ccc1Cl)=O)c1-n2cccc2)nn1-c1ccccc1

InChI

InChI=1S/C23H21ClN4O/c1-17-21(22(29)25-14-13-18-9-11-19(24)12-10-18)23(27-15-5-6-16-27)28(26-17)20-7-3-2-4-8-20/h2-12,15-16H,13-14H2,1H3,(H,25,29)

InChI Key

FATMDFLGFQDZQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14804787

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.9

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.215

Distribution Coefficient, logD

4.215

Water Solubility, LogSw

-4.85

Polar Surface Area

41.703

Acid Dissociation Constant (pKa)

14.49

Base Dissociation Constant (pKb)

0.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

C883-0381 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

CNS targets activity set (6557 compounds)

SH2 Library (10483 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Endocrine
  • Nervous system
Mechanism of action:
  • PPI modulators
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with C883-0381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C883-0381?
Check Price and Availability of C883-0381, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C883-0381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C883-0381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C883-0381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C883-0381 available by request