C919-0521 Screening compound: N~1~-(1,3-benzodioxol-5-yl)-3-(2,4,8,10-tetramethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)propanamide

C919-0521 Screening compound: N~1~-(1,3-benzodioxol-5-yl)-3-(2,4,8,10-tetramethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)propanamide
C919-0521 Screening compound: N~1~-(1,3-benzodioxol-5-yl)-3-(2,4,8,10-tetramethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C919-0521
N~1~-(1,3-benzodioxol-5-yl)-3-(2,4,8,10-tetramethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C919-0521

Molecular Formula

C23H23N5O3 (C23 H23 N5 O3)

Compound Name

N~1~-(1,3-benzodioxol-5-yl)-3-(2,4,8,10-tetramethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)propanamide

IUPAC name

N-(2H-13-benzodioxol-5-yl)-3-{461113-tetramethyl-37810-tetraazatricyclo[7.4.0.0^{27}]trideca-13581012-hexaen-5-yl}propanamide

SMILES

Cc1cc(C)nc2nn3c(C)c(CCC(Nc(cc4)cc5c4OCO5)=O)c(C)nc3c12

InChI

InChI=1S/C23H23N5O3/c1-12-9-13(2)24-22-21(12)23-25-14(3)17(15(4)28(23)27-22)6-8-20(29)26-16-5-7-18-19(10-16)31-11-30-18/h5,7,9-10H,6,8,11H2,1-4H3,(H,26,29)

InChI Key

HBHLZJPEWUYYED-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14808764

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.302

Distribution Coefficient, logD

3.302

Water Solubility, LogSw

-3.68

Polar Surface Area

69.995

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

4.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

C919-0521 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C919-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C919-0521?
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What is the minimum amount of C919-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C919-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C919-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C919-0521 available by request