CM4146-1530 Screening compound: 1-(5-chloro-2-methoxybenzoyl)-4-[5-(propan-2-yl)-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-4-yl]piperidine

CM4146-1530 Screening compound: 1-(5-chloro-2-methoxybenzoyl)-4-[5-(propan-2-yl)-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-4-yl]piperidine
CM4146-1530 Screening compound: 1-(5-chloro-2-methoxybenzoyl)-4-[5-(propan-2-yl)-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-4-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound CM4146-1530
1-(5-chloro-2-methoxybenzoyl)-4-[5-(propan-2-yl)-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-4-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM4146-1530

Molecular Formula

C22H29ClN4O2 (C22 H29 ClN4 O2)

Compound Name

1-(5-chloro-2-methoxybenzoyl)-4-[5-(propan-2-yl)-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-4-yl]piperidine

IUPAC name

1-(5-chloro-2-methoxybenzoyl)-4-[5-(propan-2-yl)-1H4H5H6H7H-imidazo[45-c]pyridin-4-yl]piperidine

SMILES

CC(C)N(CC1)C(C(CC2)CCN2C(c(cc(cc2)Cl)c2OC)=O)c2c1[nH]cn2

InChI

InChI=1S/C22H29ClN4O2/c1-14(2)27-11-8-18-20(25-13-24-18)21(27)15-6-9-26(10-7-15)22(28)17-12-16(23)4-5-19(17)29-3/h4-5,12-15,21H,6-11H2,1-3H3,(H,24,25)/t21-/m0/s1

InChI Key

APSNVTAJWCXJBP-NRFANRHFSA-N

MDL Number (MFCD)

MFCD31955126

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.95

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.334

Distribution Coefficient, logD

-0.527

Water Solubility, LogSw

-3.68

Polar Surface Area

50.738

Acid Dissociation Constant (pKa)

14.25

Base Dissociation Constant (pKb)

11.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.54

CM4146-1530 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Ion Channels Focused Library (26372 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with CM4146-1530 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM4146-1530?
Check Price and Availability of CM4146-1530, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM4146-1530 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM4146-1530
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM4146-1530
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM4146-1530 available by request