CM4527-0642 Screening compound: N-methyl-1-phenyl-2-(propan-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide

CM4527-0642 Screening compound: N-methyl-1-phenyl-2-(propan-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
CM4527-0642 Screening compound: N-methyl-1-phenyl-2-(propan-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound CM4527-0642
N-methyl-1-phenyl-2-(propan-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

CM4527-0642

Molecular Formula

C18H27N3O (C18 H27 N3 O)

Compound Name

N-methyl-1-phenyl-2-(propan-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide

IUPAC name

N-methyl-1-phenyl-2-(propan-2-yl)-27-diazaspiro[3.5]nonane-7-carboxamide

SMILES

CC(C)N(CC1(CC2)CCN2C(NC)=O)C1c1ccccc1

InChI

InChI=1S/C18H27N3O/c1-14(2)21-13-18(16(21)15-7-5-4-6-8-15)9-11-20(12-10-18)17(22)19-3/h4-8,14,16H,9-13H2,1-3H3,(H,19,22)/t16-/m1/s1

InChI Key

RQAOSULHUDUVAA-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD30467538

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

301.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.655

Distribution Coefficient, logD

-1.263

Water Solubility, LogSw

-2.88

Polar Surface Area

30.747

Acid Dissociation Constant (pKa)

16.65

Base Dissociation Constant (pKb)

11.32

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.11

CM4527-0642 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS MPO Library (28609 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with CM4527-0642 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound CM4527-0642?
Check Price and Availability of CM4527-0642, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of CM4527-0642 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for CM4527-0642
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for CM4527-0642
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of CM4527-0642 available by request