D015-0176 Screening compound: 3-(4-chlorophenyl)-6-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

D015-0176 Screening compound: 3-(4-chlorophenyl)-6-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine
D015-0176 Screening compound: 3-(4-chlorophenyl)-6-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D015-0176
3-(4-chlorophenyl)-6-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D015-0176

Molecular Formula

C19H12ClF3N4 (C19 H12 ClF3 N4)

Compound Name

3-(4-chlorophenyl)-6-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

3-(4-chlorophenyl)-6-phenyl-2-(trifluoromethyl)pyrazolo[15-a]pyrimidin-7-amine

SMILES

Nc(n1nc(C(F)(F)F)c(-c(cc2)ccc2Cl)c1nc1)c1-c1ccccc1

InChI

InChI=1S/C19H12ClF3N4/c20-13-8-6-12(7-9-13)15-16(19(21,22)23)26-27-17(24)14(10-25-18(15)27)11-4-2-1-3-5-11/h1-10H,24H2

InChI Key

CESHFVAXEPPVEK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09586678

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.78

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.733

Distribution Coefficient, logD

4.730

Water Solubility, LogSw

-5.41

Polar Surface Area

39.962

Acid Dissociation Constant (pKa)

19.64

Base Dissociation Constant (pKb)

5.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

D015-0176 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D015-0176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D015-0176?
Check Price and Availability of D015-0176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D015-0176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D015-0176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D015-0176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D015-0176 available by request