D032-0002 Screening compound: 4-(4-chlorophenyl)pyrimido[4,5-b]indolizine-10-carbonitrile

D032-0002 Screening compound: 4-(4-chlorophenyl)pyrimido[4,5-b]indolizine-10-carbonitrile
D032-0002 Screening compound: 4-(4-chlorophenyl)pyrimido[4,5-b]indolizine-10-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound D032-0002
4-(4-chlorophenyl)pyrimido[4,5-b]indolizine-10-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D032-0002

Molecular Formula

C17H9ClN4 (C17 H9 ClN4)

Compound Name

4-(4-chlorophenyl)pyrimido[4,5-b]indolizine-10-carbonitrile

IUPAC name

4-(4-chlorophenyl)pyrimido[45-b]indolizine-10-carbonitrile

SMILES

N#Cc1c(cccc2)n2c2c1ncnc2-c(cc1)ccc1Cl

InChI

InChI=1S/C17H9ClN4/c18-12-6-4-11(5-7-12)15-17-16(21-10-20-15)13(9-19)14-3-1-2-8-22(14)17/h1-8,10H

InChI Key

QYPXOQMSCTZZGU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09058238

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

304.74

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.303

Distribution Coefficient, logD

3.303

Water Solubility, LogSw

-4.25

Polar Surface Area

37.068

Acid Dissociation Constant (pKa)

14.00

Base Dissociation Constant (pKb)

4.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

D032-0002 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Immunological Library (6760 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Akt-Targeted Library (14764 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Immune system
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Nuclear receptors
  • Kinases
  • Others
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D032-0002 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D032-0002?
Check Price and Availability of D032-0002, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D032-0002 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D032-0002
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D032-0002
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D032-0002 available by request