D052-0154 Screening compound: 6-methyl-3-(2-pyridyl)pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione

D052-0154 Screening compound: 6-methyl-3-(2-pyridyl)pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione
D052-0154 Screening compound: 6-methyl-3-(2-pyridyl)pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D052-0154
6-methyl-3-(2-pyridyl)pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D052-0154

Molecular Formula

C11H8N6O2 (C11 H8 N6 O2)

Compound Name

6-methyl-3-(2-pyridyl)pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione

IUPAC name

6-methyl-3-(pyridin-2-yl)-5H6H7H8H-pyrimido[54-e][124]triazine-57-dione

SMILES

CN(C(c1c(N2)nnc(-c3ncccc3)n1)=O)C2=O

InChI

InChI=1S/C11H8N6O2/c1-17-10(18)7-9(14-11(17)19)16-15-8(13-7)6-4-2-3-5-12-6/h2-5H,1H3,(H,14,16,19)

InChI Key

KBRNFEOSBIPBFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00425847

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

256.22

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.025

Distribution Coefficient, logD

-0.232

Water Solubility, LogSw

-1.60

Polar Surface Area

82.429

Acid Dissociation Constant (pKa)

7.49

Base Dissociation Constant (pKb)

2.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.09

D052-0154 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D052-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D052-0154?
Check Price and Availability of D052-0154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D052-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D052-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D052-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D052-0154 available by request