D090-0024 Screening compound: 4-cyclohexyl-10-methoxy-2,4,5,6-tetrahydro-1H-pyrazino[1,2,3-lm]beta-carboline

D090-0024 Screening compound: 4-cyclohexyl-10-methoxy-2,4,5,6-tetrahydro-1H-pyrazino[1,2,3-lm]beta-carboline
D090-0024 Screening compound: 4-cyclohexyl-10-methoxy-2,4,5,6-tetrahydro-1H-pyrazino[1,2,3-lm]beta-carboline alternative view

Chemical Structure Depiction of ChemDiv screening compound D090-0024
4-cyclohexyl-10-methoxy-2,4,5,6-tetrahydro-1H-pyrazino[1,2,3-lm]beta-carboline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D090-0024

Molecular Formula

C20H25N3O (C20 H25 N3 O)

Compound Name

4-cyclohexyl-10-methoxy-2,4,5,6-tetrahydro-1H-pyrazino[1,2,3-lm]beta-carboline

IUPAC name

4-cyclohexyl-12-methoxy-146-triazatetracyclo[7.6.1.0^{516}.0^{1015}]hexadeca-59(16)101214-pentaene

SMILES

COc(cc1)cc2c1n(CC1)c3c2CCN=C3N1C1CCCCC1

InChI

InChI=1S/C20H25N3O/c1-24-15-7-8-18-17(13-15)16-9-10-21-20-19(16)23(18)12-11-22(20)14-5-3-2-4-6-14/h7-8,13-14H,2-6,9-12H2,1H3

InChI Key

GLGVXUZRAPAKTI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02071759

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

323.44

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.817

Distribution Coefficient, logD

3.689

Water Solubility, LogSw

-4.74

Polar Surface Area

19.753

Acid Dissociation Constant (pKa)

24.29

Base Dissociation Constant (pKb)

8.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.00

D090-0024 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D090-0024 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D090-0024?
Check Price and Availability of D090-0024, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D090-0024 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D090-0024
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D090-0024
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D090-0024 available by request