D090-0063 Screening compound: N-biphenyl-4-yl-3-oxo-1,2,3,5-tetrahydropyrido[1,2-a]benzimidazole-4-carboxamide

D090-0063 Screening compound: N-biphenyl-4-yl-3-oxo-1,2,3,5-tetrahydropyrido[1,2-a]benzimidazole-4-carboxamide
D090-0063 Screening compound: N-biphenyl-4-yl-3-oxo-1,2,3,5-tetrahydropyrido[1,2-a]benzimidazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D090-0063
N-biphenyl-4-yl-3-oxo-1,2,3,5-tetrahydropyrido[1,2-a]benzimidazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D090-0063

Molecular Formula

C24H19N3O2 (C24 H19 N3 O2)

Compound Name

N-biphenyl-4-yl-3-oxo-1,2,3,5-tetrahydropyrido[1,2-a]benzimidazole-4-carboxamide

IUPAC name

N-{[11'-biphenyl]-4-yl}-11-oxo-18-diazatricyclo[7.4.0.0^{27}]trideca-2469-tetraene-10-carboxamide

SMILES

O=C(C(C(CC1)=O)=C2N1c(cccc1)c1N2)Nc(cc1)ccc1-c1ccccc1

InChI

InChI=1S/C24H19N3O2/c28-21-14-15-27-20-9-5-4-8-19(20)26-23(27)22(21)24(29)25-18-12-10-17(11-13-18)16-6-2-1-3-7-16/h1-13,26H,14-15H2,(H,25,29)

InChI Key

FIWXVUIXNSAMBX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01455310

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.572

Distribution Coefficient, logD

4.572

Water Solubility, LogSw

-4.52

Polar Surface Area

49.840

Acid Dissociation Constant (pKa)

10.74

Base Dissociation Constant (pKb)

-0.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

D090-0063 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

DGK Inhibitors Library (10558 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D090-0063 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D090-0063?
Check Price and Availability of D090-0063, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D090-0063 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D090-0063
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D090-0063
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D090-0063 available by request