D124-0010 Screening compound: 8-hydroxy-7-(propan-2-yl)-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazin-6-one

D124-0010 Screening compound: 8-hydroxy-7-(propan-2-yl)-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazin-6-one
D124-0010 Screening compound: 8-hydroxy-7-(propan-2-yl)-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D124-0010
8-hydroxy-7-(propan-2-yl)-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D124-0010

Molecular Formula

C10H14N2O2S (C10 H14 N2 O2 S)

Compound Name

8-hydroxy-7-(propan-2-yl)-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazin-6-one

IUPAC name

8-hydroxy-7-(propan-2-yl)-2H3H4H6H-pyrimido[21-b][13]thiazin-6-one

SMILES

CC(C)C(C(N(CCCS1)C1=N1)=O)=C1O

InChI

InChI=1S/C10H14N2O2S/c1-6(2)7-8(13)11-10-12(9(7)14)4-3-5-15-10/h6,13H,3-5H2,1-2H3

InChI Key

LOBIJOACXURRLP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08684902

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

226.3

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.315

Distribution Coefficient, logD

-2.065

Water Solubility, LogSw

-1.46

Polar Surface Area

42.162

Acid Dissociation Constant (pKa)

4.02

Base Dissociation Constant (pKb)

0.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

D124-0010 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Fragments Library (11262 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Fragments
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D124-0010 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D124-0010?
Check Price and Availability of D124-0010, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D124-0010 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D124-0010
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D124-0010
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D124-0010 available by request