D183-0126 Screening compound: 6-({4-[(4-methylphenyl)amino]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}oxy)pyridazin-3-ol

D183-0126 Screening compound: 6-({4-[(4-methylphenyl)amino]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}oxy)pyridazin-3-ol
D183-0126 Screening compound: 6-({4-[(4-methylphenyl)amino]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}oxy)pyridazin-3-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound D183-0126
6-({4-[(4-methylphenyl)amino]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}oxy)pyridazin-3-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D183-0126

Molecular Formula

C18H19N7O3 (C18 H19 N7 O3)

Compound Name

6-({4-[(4-methylphenyl)amino]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}oxy)pyridazin-3-ol

IUPAC name

6-({4-[(4-methylphenyl)amino]-6-(morpholin-4-yl)-135-triazin-2-yl}oxy)pyridazin-3-ol

SMILES

Cc(cc1)ccc1Nc1nc(N2CCOCC2)nc(Oc(cc2)nnc2O)n1

InChI

InChI=1S/C18H19N7O3/c1-12-2-4-13(5-3-12)19-16-20-17(25-8-10-27-11-9-25)22-18(21-16)28-15-7-6-14(26)23-24-15/h2-7H,8-11H2,1H3,(H,23,26)(H,19,20,21,22)

InChI Key

NHTLHSJCJLIHIJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06177843

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.093

Distribution Coefficient, logD

2.703

Water Solubility, LogSw

-3.24

Polar Surface Area

95.890

Acid Dissociation Constant (pKa)

7.24

Base Dissociation Constant (pKb)

2.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

D183-0126 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D183-0126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D183-0126?
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What is the minimum amount of D183-0126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D183-0126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D183-0126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D183-0126 available by request