D185-0030 Screening compound: 2-[2-(piperidin-1-yl)ethyl]-1-(thiophene-2-carbonyl)piperidine

D185-0030 Screening compound: 2-[2-(piperidin-1-yl)ethyl]-1-(thiophene-2-carbonyl)piperidine
D185-0030 Screening compound: 2-[2-(piperidin-1-yl)ethyl]-1-(thiophene-2-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D185-0030
2-[2-(piperidin-1-yl)ethyl]-1-(thiophene-2-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D185-0030

Molecular Formula

C17H26N2OS (C17 H26 N2 OS)

Compound Name

2-[2-(piperidin-1-yl)ethyl]-1-(thiophene-2-carbonyl)piperidine

IUPAC name

2-[2-(piperidin-1-yl)ethyl]-1-(thiophene-2-carbonyl)piperidine

SMILES

O=C(c1cccs1)N1C(CCN2CCCCC2)CCCC1

InChI

InChI=1S/C17H26N2OS/c20-17(16-8-6-14-21-16)19-12-5-2-7-15(19)9-13-18-10-3-1-4-11-18/h6,8,14-15H,1-5,7,9-13H2/t15-/m1/s1

InChI Key

CBWLDACJAQNNJU-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD12918239

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

306.47

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

3.299

Distribution Coefficient, logD

1.512

Water Solubility, LogSw

-3.35

Polar Surface Area

21.262

Acid Dissociation Constant (pKa)

27.87

Base Dissociation Constant (pKb)

9.18

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.60

D185-0030 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with D185-0030 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D185-0030?
Check Price and Availability of D185-0030, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D185-0030 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D185-0030
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D185-0030
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D185-0030 available by request