D187-0026 Screening compound: 3-(2-{[4-(dimethylamino)-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]oxy}ethyl)-1-phenylurea

D187-0026 Screening compound: 3-(2-{[4-(dimethylamino)-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]oxy}ethyl)-1-phenylurea
D187-0026 Screening compound: 3-(2-{[4-(dimethylamino)-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]oxy}ethyl)-1-phenylurea alternative view

Chemical Structure Depiction of ChemDiv screening compound D187-0026
3-(2-{[4-(dimethylamino)-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]oxy}ethyl)-1-phenylurea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D187-0026

Molecular Formula

C18H25N7O3 (C18 H25 N7 O3)

Compound Name

3-(2-{[4-(dimethylamino)-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]oxy}ethyl)-1-phenylurea

IUPAC name

3-(2-{[4-(dimethylamino)-6-(morpholin-4-yl)-135-triazin-2-yl]oxy}ethyl)-1-phenylurea

SMILES

CN(C)c1nc(OCCNC(Nc2ccccc2)=O)nc(N2CCOCC2)n1

InChI

InChI=1S/C18H25N7O3/c1-24(2)15-21-16(25-9-12-27-13-10-25)23-18(22-15)28-11-8-19-17(26)20-14-6-4-3-5-7-14/h3-7H,8-13H2,1-2H3,(H2,19,20,26)

InChI Key

PYSDDDLOLFMHOC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03722772

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.038

Distribution Coefficient, logD

3.038

Water Solubility, LogSw

-3.36

Polar Surface Area

82.810

Acid Dissociation Constant (pKa)

13.82

Base Dissociation Constant (pKb)

2.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

D187-0026 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

PI3K-Targeted Library (17255 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D187-0026 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D187-0026?
Check Price and Availability of D187-0026, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D187-0026 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D187-0026
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D187-0026
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D187-0026 available by request