D203-0159 Screening compound: 5-[1-(4-methylbenzenesulfonyl)piperidin-4-yl]-3-{[4-(trifluoromethoxy)phenyl]methyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol

D203-0159 Screening compound: 5-[1-(4-methylbenzenesulfonyl)piperidin-4-yl]-3-{[4-(trifluoromethoxy)phenyl]methyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol
D203-0159 Screening compound: 5-[1-(4-methylbenzenesulfonyl)piperidin-4-yl]-3-{[4-(trifluoromethoxy)phenyl]methyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound D203-0159
5-[1-(4-methylbenzenesulfonyl)piperidin-4-yl]-3-{[4-(trifluoromethoxy)phenyl]methyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D203-0159

Molecular Formula

C24H23F3N6O4S (C24 H23 F3 N6 O4 S)

Compound Name

5-[1-(4-methylbenzenesulfonyl)piperidin-4-yl]-3-{[4-(trifluoromethoxy)phenyl]methyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol

IUPAC name

5-[1-(4-methylbenzenesulfonyl)piperidin-4-yl]-3-{[4-(trifluoromethoxy)phenyl]methyl}-3H-[123]triazolo[45-d]pyrimidin-7-ol

SMILES

Cc(cc1)ccc1S(N(CC1)CCC1c1nc(O)c2nnn(Cc(cc3)ccc3OC(F)(F)F)c2n1)(=O)=O

InChI

InChI=1S/C24H23F3N6O4S/c1-15-2-8-19(9-3-15)38(35,36)32-12-10-17(11-13-32)21-28-22-20(23(34)29-21)30-31-33(22)14-16-4-6-18(7-5-16)37-24(25,26)27/h2-9,17H,10-14H2,1H3,(H,28,29,34)

InChI Key

UWCNEUTXJRUEHW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14813865

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

548.55

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

4.312

Distribution Coefficient, logD

3.858

Water Solubility, LogSw

-4.19

Polar Surface Area

100.201

Acid Dissociation Constant (pKa)

7.13

Base Dissociation Constant (pKb)

1.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

D203-0159 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D203-0159 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D203-0159?
Check Price and Availability of D203-0159, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D203-0159 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D203-0159
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D203-0159
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D203-0159 available by request