D216-0344 Screening compound: 4-(3-{[4-(pyrazin-2-yl)piperazin-1-yl]sulfonyl}benzenesulfonyl)morpholine

D216-0344 Screening compound: 4-(3-{[4-(pyrazin-2-yl)piperazin-1-yl]sulfonyl}benzenesulfonyl)morpholine
D216-0344 Screening compound: 4-(3-{[4-(pyrazin-2-yl)piperazin-1-yl]sulfonyl}benzenesulfonyl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound D216-0344
4-(3-{[4-(pyrazin-2-yl)piperazin-1-yl]sulfonyl}benzenesulfonyl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D216-0344

Molecular Formula

C18H23N5O5S2 (C18 H23 N5 O5 S2)

Compound Name

4-(3-{[4-(pyrazin-2-yl)piperazin-1-yl]sulfonyl}benzenesulfonyl)morpholine

IUPAC name

4-(3-{[4-(pyrazin-2-yl)piperazin-1-yl]sulfonyl}benzenesulfonyl)morpholine

SMILES

O=S(c1cccc(S(N2CCOCC2)(=O)=O)c1)(N(CC1)CCN1c1nccnc1)=O

InChI

InChI=1S/C18H23N5O5S2/c24-29(25,22-8-6-21(7-9-22)18-15-19-4-5-20-18)16-2-1-3-17(14-16)30(26,27)23-10-12-28-13-11-23/h1-5,14-15H,6-13H2

InChI Key

NFAKHOYKBWSKKK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14814356

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.54

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.096

Distribution Coefficient, logD

1.096

Water Solubility, LogSw

-1.79

Polar Surface Area

92.858

Acid Dissociation Constant (pKa)

24.54

Base Dissociation Constant (pKb)

2.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

D216-0344 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Purinergic Library (3321 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • GPCR
  • Ion Channels
  • Kinases
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D216-0344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D216-0344?
Check Price and Availability of D216-0344, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D216-0344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D216-0344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D216-0344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D216-0344 available by request