D223-0360 Screening compound: methyl 4-[1-(4-fluorophenyl)-4-oxo-1,4-dihydropyridazine-3-amido]benzoate

D223-0360 Screening compound: methyl 4-[1-(4-fluorophenyl)-4-oxo-1,4-dihydropyridazine-3-amido]benzoate
D223-0360 Screening compound: methyl 4-[1-(4-fluorophenyl)-4-oxo-1,4-dihydropyridazine-3-amido]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound D223-0360
methyl 4-[1-(4-fluorophenyl)-4-oxo-1,4-dihydropyridazine-3-amido]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D223-0360

Molecular Formula

C19H14FN3O4 (C19 H14 FN3 O4)

Compound Name

methyl 4-[1-(4-fluorophenyl)-4-oxo-1,4-dihydropyridazine-3-amido]benzoate

IUPAC name

methyl 4-[1-(4-fluorophenyl)-4-oxo-14-dihydropyridazine-3-amido]benzoate

SMILES

COC(c(cc1)ccc1NC(C(C(C=C1)=O)=NN1c(cc1)ccc1F)=O)=O

InChI

InChI=1S/C19H14FN3O4/c1-27-19(26)12-2-6-14(7-3-12)21-18(25)17-16(24)10-11-23(22-17)15-8-4-13(20)5-9-15/h2-11H,1H3,(H,21,25)

InChI Key

MCUJYJBIOVVMAJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07642734

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.34

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.980

Distribution Coefficient, logD

2.784

Water Solubility, LogSw

-3.66

Polar Surface Area

70.914

Acid Dissociation Constant (pKa)

7.64

Base Dissociation Constant (pKb)

-1.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

D223-0360 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D223-0360 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D223-0360?
Check Price and Availability of D223-0360, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D223-0360 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D223-0360
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D223-0360
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D223-0360 available by request