D224-0063 Screening compound: 4-[1-(3,4-dimethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]pyridine

D224-0063 Screening compound: 4-[1-(3,4-dimethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]pyridine
D224-0063 Screening compound: 4-[1-(3,4-dimethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound D224-0063
4-[1-(3,4-dimethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D224-0063

Molecular Formula

C21H17F3N4 (C21 H17 F3 N4)

Compound Name

4-[1-(3,4-dimethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]pyridine

IUPAC name

4-[1-(34-dimethylphenyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]pyridine

SMILES

Cc(c1c(C(F)(F)F)cc(-c2ccncc2)nc11)nn1-c1cc(C)c(C)cc1

InChI

InChI=1S/C21H17F3N4/c1-12-4-5-16(10-13(12)2)28-20-19(14(3)27-28)17(21(22,23)24)11-18(26-20)15-6-8-25-9-7-15/h4-11H,1-3H3

InChI Key

MZWSSJCQLDMNSW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07125936

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.39

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.649

Distribution Coefficient, logD

5.648

Water Solubility, LogSw

-5.90

Polar Surface Area

32.791

Acid Dissociation Constant (pKa)

27.62

Base Dissociation Constant (pKb)

4.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

D224-0063 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Aging Library (44940 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D224-0063 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D224-0063?
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What is the minimum amount of D224-0063 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D224-0063
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D224-0063
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D224-0063 available by request