D268-0449 Screening compound: N-(2-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine

D268-0449 Screening compound: N-(2-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine
D268-0449 Screening compound: N-(2-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D268-0449
N-(2-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D268-0449

Molecular Formula

C17H20N6O2 (C17 H20 N6 O2)

Compound Name

N-(2-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine

IUPAC name

N-(2-methoxyphenyl)-6-(4-methylpiperidin-1-yl)-[125]oxadiazolo[34-b]pyrazin-5-amine

SMILES

CC(CC1)CCN1c1nc2nonc2nc1Nc(cccc1)c1OC

InChI

InChI=1S/C17H20N6O2/c1-11-7-9-23(10-8-11)17-16(19-14-15(20-17)22-25-21-14)18-12-5-3-4-6-13(12)24-2/h3-6,11H,7-10H2,1-2H3,(H,18,19,21)

InChI Key

BVIPWOJDVXCPCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01460741

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.625

Distribution Coefficient, logD

4.625

Water Solubility, LogSw

-4.33

Polar Surface Area

75.312

Acid Dissociation Constant (pKa)

13.35

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.20

D268-0449 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Aging Library (44940 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D268-0449 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D268-0449?
Check Price and Availability of D268-0449, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D268-0449 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D268-0449
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D268-0449
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D268-0449 available by request