D274-0160 Screening compound: 1-ethyl-6'-methoxy-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]

D274-0160 Screening compound: 1-ethyl-6'-methoxy-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]
D274-0160 Screening compound: 1-ethyl-6'-methoxy-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] alternative view

Chemical Structure Depiction of ChemDiv screening compound D274-0160
1-ethyl-6'-methoxy-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D274-0160

Molecular Formula

C18H25N3O (C18 H25 N3 O)

Compound Name

1-ethyl-6'-methoxy-2',3',4',9'-tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole]

IUPAC name

1-ethyl-6'-methoxy-2'3'4'9'-tetrahydrospiro[piperidine-41'-pyrido[34-b]indole]

SMILES

CCN(CC1)CCC11NCCc2c1[nH]c(cc1)c2cc1OC

InChI

InChI=1S/C18H25N3O/c1-3-21-10-7-18(8-11-21)17-14(6-9-19-18)15-12-13(22-2)4-5-16(15)20-17/h4-5,12,19-20H,3,6-11H2,1-2H3

InChI Key

XJKMLZDJTHARRX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26967629

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

299.42

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.364

Distribution Coefficient, logD

0.263

Water Solubility, LogSw

-2.65

Polar Surface Area

33.728

Acid Dissociation Constant (pKa)

18.70

Base Dissociation Constant (pKb)

9.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.56

D274-0160 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

3D-Fragment Library (4274 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Spiro Library (21655 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • 3D
  • Fragments
  • Cyclic compounds
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D274-0160 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D274-0160?
Check Price and Availability of D274-0160, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D274-0160 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D274-0160
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D274-0160
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D274-0160 available by request