D274-0187 Screening compound: 1-(pyrazin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide

D274-0187 Screening compound: 1-(pyrazin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide
D274-0187 Screening compound: 1-(pyrazin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D274-0187
1-(pyrazin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D274-0187

Molecular Formula

C18H23N5O3S (C18 H23 N5 O3 S)

Compound Name

1-(pyrazin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide

IUPAC name

1-(pyrazin-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]piperidine-4-carboxamide

SMILES

NS(c1ccc(CCNC(C(CC2)CCN2c2nccnc2)=O)cc1)(=O)=O

InChI

InChI=1S/C18H23N5O3S/c19-27(25,26)16-3-1-14(2-4-16)5-8-22-18(24)15-6-11-23(12-7-15)17-13-20-9-10-21-17/h1-4,9-10,13,15H,5-8,11-12H2,(H,22,24)(H2,19,25,26)

InChI Key

CJSUUAPDLZBIRV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14816430

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.48

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.406

Distribution Coefficient, logD

0.406

Water Solubility, LogSw

-1.90

Polar Surface Area

96.578

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

8.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

D274-0187 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with D274-0187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D274-0187?
Check Price and Availability of D274-0187, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D274-0187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D274-0187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D274-0187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D274-0187 available by request