D278-0221 Screening compound: 2-methyl-N-(4-methylphenyl)-6-phenylpyrimidin-4-amine

D278-0221 Screening compound: 2-methyl-N-(4-methylphenyl)-6-phenylpyrimidin-4-amine
D278-0221 Screening compound: 2-methyl-N-(4-methylphenyl)-6-phenylpyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0221
2-methyl-N-(4-methylphenyl)-6-phenylpyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0221

Molecular Formula

C18H17N3 (C18 H17 N3)

Compound Name

2-methyl-N-(4-methylphenyl)-6-phenylpyrimidin-4-amine

IUPAC name

2-methyl-N-(4-methylphenyl)-6-phenylpyrimidin-4-amine

SMILES

Cc(cc1)ccc1Nc1nc(C)nc(-c2ccccc2)c1

InChI

InChI=1S/C18H17N3/c1-13-8-10-16(11-9-13)21-18-12-17(19-14(2)20-18)15-6-4-3-5-7-15/h3-12H,1-2H3,(H,19,20,21)

InChI Key

MXJBFFPMFAENPX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09058010

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

275.35

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.973

Distribution Coefficient, logD

4.494

Water Solubility, LogSw

-4.67

Polar Surface Area

27.630

Acid Dissociation Constant (pKa)

19.34

Base Dissociation Constant (pKb)

7.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D278-0221 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Aging Library (44940 compounds)

CNS BBB Library (22607 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D278-0221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0221?
Check Price and Availability of D278-0221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0221 available by request