D278-0580 Screening compound: 4-[(2-methyl-6-phenylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

D278-0580 Screening compound: 4-[(2-methyl-6-phenylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide
D278-0580 Screening compound: 4-[(2-methyl-6-phenylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0580
4-[(2-methyl-6-phenylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0580

Molecular Formula

C22H19N5O2S (C22 H19 N5 O2 S)

Compound Name

4-[(2-methyl-6-phenylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

IUPAC name

4-[(2-methyl-6-phenylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

SMILES

Cc1nc(-c2ccccc2)cc(Nc(cc2)ccc2S(Nc2ncccc2)(=O)=O)n1

InChI

InChI=1S/C22H19N5O2S/c1-16-24-20(17-7-3-2-4-8-17)15-22(25-16)26-18-10-12-19(13-11-18)30(28,29)27-21-9-5-6-14-23-21/h2-15H,1H3,(H,23,27)(H,24,25,26)

InChI Key

COUBNXKLBCGXDW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09058064

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.277

Distribution Coefficient, logD

3.799

Water Solubility, LogSw

-4.36

Polar Surface Area

77.895

Acid Dissociation Constant (pKa)

7.77

Base Dissociation Constant (pKb)

7.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.50

D278-0580 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Ion Channels Focused Library (26372 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with D278-0580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0580?
Check Price and Availability of D278-0580, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0580 available by request