D278-0741 Screening compound: ethyl 4-methyl-2-(2-{[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}acetamido)-1,3-thiazole-5-carboxylate

D278-0741 Screening compound: ethyl 4-methyl-2-(2-{[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}acetamido)-1,3-thiazole-5-carboxylate
D278-0741 Screening compound: ethyl 4-methyl-2-(2-{[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}acetamido)-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0741
ethyl 4-methyl-2-(2-{[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}acetamido)-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0741

Molecular Formula

C19H17N5O3S2 (C19 H17 N5 O3 S2)

Compound Name

ethyl 4-methyl-2-(2-{[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}acetamido)-1,3-thiazole-5-carboxylate

IUPAC name

ethyl 4-methyl-2-(2-{[124]triazolo[43-a]quinolin-1-ylsulfanyl}acetamido)-13-thiazole-5-carboxylate

SMILES

CCOC(c1c(C)nc(NC(CSc2nnc3n2c(cccc2)c2cc3)=O)s1)=O

InChI

InChI=1S/C19H17N5O3S2/c1-3-27-17(26)16-11(2)20-18(29-16)21-15(25)10-28-19-23-22-14-9-8-12-6-4-5-7-13(12)24(14)19/h4-9H,3,10H2,1-2H3,(H,20,21,25)

InChI Key

QYSSTZZFPKHUBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09057947

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.575

Distribution Coefficient, logD

3.535

Water Solubility, LogSw

-3.70

Polar Surface Area

75.608

Acid Dissociation Constant (pKa)

8.42

Base Dissociation Constant (pKb)

2.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

D278-0741 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with D278-0741 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0741?
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What is the minimum amount of D278-0741 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0741
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0741
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0741 available by request