D280-0510 Screening compound: 10-(1H-indol-3-yl)-5-(4-methoxyphenyl)-1,3,7,7-tetramethyl-1,7,8,10-tetrahydro-2H-pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]oxazine-2,4(3H)-dione

D280-0510 Screening compound: 10-(1H-indol-3-yl)-5-(4-methoxyphenyl)-1,3,7,7-tetramethyl-1,7,8,10-tetrahydro-2H-pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]oxazine-2,4(3H)-dione
D280-0510 Screening compound: 10-(1H-indol-3-yl)-5-(4-methoxyphenyl)-1,3,7,7-tetramethyl-1,7,8,10-tetrahydro-2H-pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]oxazine-2,4(3H)-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D280-0510
10-(1H-indol-3-yl)-5-(4-methoxyphenyl)-1,3,7,7-tetramethyl-1,7,8,10-tetrahydro-2H-pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]oxazine-2,4(3H)-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D280-0510

Molecular Formula

C28H28N4O4 (C28 H28 N4 O4)

Compound Name

10-(1H-indol-3-yl)-5-(4-methoxyphenyl)-1,3,7,7-tetramethyl-1,7,8,10-tetrahydro-2H-pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]oxazine-2,4(3H)-dione

IUPAC name

13-(1H-indol-3-yl)-8-(4-methoxyphenyl)-351010-tetramethyl-12-oxa-359-triazatricyclo[7.4.0.0^{27}]trideca-17-diene-46-dione

SMILES

CC(C)(COC(c1c[nH]c2c1cccc2)c1c2N(C)C(N3C)=O)n1c(-c(cc1)ccc1OC)c2C3=O

InChI

InChI=1S/C28H28N4O4/c1-28(2)15-36-25(19-14-29-20-9-7-6-8-18(19)20)24-23-21(26(33)31(4)27(34)30(23)3)22(32(24)28)16-10-12-17(35-5)13-11-16/h6-14,25,29H,15H2,1-5H3/t25-/m0/s1

InChI Key

KCQUUOHBGIRUBG-VWLOTQADSA-N

MDL Number (MFCD)

MFCD06792679

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.499

Distribution Coefficient, logD

4.499

Water Solubility, LogSw

-4.47

Polar Surface Area

58.717

Acid Dissociation Constant (pKa)

18.39

Base Dissociation Constant (pKb)

-0.62

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.60

D280-0510 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with D280-0510 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D280-0510?
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What is the minimum amount of D280-0510 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D280-0510
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D280-0510
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D280-0510 available by request