D282-0126 Screening compound: ethyl 2-[2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)-1,3-thiazol-4-yl]acetate

D282-0126 Screening compound: ethyl 2-[2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)-1,3-thiazol-4-yl]acetate
D282-0126 Screening compound: ethyl 2-[2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)-1,3-thiazol-4-yl]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound D282-0126
ethyl 2-[2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)-1,3-thiazol-4-yl]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D282-0126

Molecular Formula

C18H17N3O3S2 (C18 H17 N3 O3 S2)

Compound Name

ethyl 2-[2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)-1,3-thiazol-4-yl]acetate

IUPAC name

ethyl 2-[2-(4-methyl-2-phenyl-13-thiazole-5-amido)-13-thiazol-4-yl]acetate

SMILES

CCOC(Cc1csc(NC(c2c(C)nc(-c3ccccc3)s2)=O)n1)=O

InChI

InChI=1S/C18H17N3O3S2/c1-3-24-14(22)9-13-10-25-18(20-13)21-16(23)15-11(2)19-17(26-15)12-7-5-4-6-8-12/h4-8,10H,3,9H2,1-2H3,(H,20,21,23)

InChI Key

QBEJZQGXEKTFCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08568368

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.181

Distribution Coefficient, logD

4.143

Water Solubility, LogSw

-4.10

Polar Surface Area

64.341

Acid Dissociation Constant (pKa)

8.44

Base Dissociation Constant (pKb)

-0.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

D282-0126 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D282-0126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D282-0126?
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What is the minimum amount of D282-0126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D282-0126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D282-0126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D282-0126 available by request