D284-0174 Screening compound: 4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol

D284-0174 Screening compound: 4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
D284-0174 Screening compound: 4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound D284-0174
4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D284-0174

Molecular Formula

C12H13ClF3NO (C12 H13 ClF3 NO)

Compound Name

4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol

IUPAC name

4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol

SMILES

OC1(CCNCC1)c(cc1)cc(C(F)(F)F)c1Cl

InChI

InChI=1S/C12H13ClF3NO/c13-10-2-1-8(7-9(10)12(14,15)16)11(18)3-5-17-6-4-11/h1-2,7,17-18H,3-6H2

InChI Key

RALRVIPTUXSBPO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00066999

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

279.69

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

2.302

Distribution Coefficient, logD

-0.778

Water Solubility, LogSw

-3.11

Polar Surface Area

27.225

Acid Dissociation Constant (pKa)

15.21

Base Dissociation Constant (pKb)

10.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

D284-0174 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Structure:
  • Fragments
Mechanism of action:
  • PPI modulators
Targets:
  • Kinases
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D284-0174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D284-0174?
Check Price and Availability of D284-0174, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D284-0174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D284-0174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D284-0174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D284-0174 available by request