D292-0266 Screening compound: 1-(1,3-benzothiazol-2-yl)-4-(4-ethylphenyl)-3-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

D292-0266 Screening compound: 1-(1,3-benzothiazol-2-yl)-4-(4-ethylphenyl)-3-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one
D292-0266 Screening compound: 1-(1,3-benzothiazol-2-yl)-4-(4-ethylphenyl)-3-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D292-0266
1-(1,3-benzothiazol-2-yl)-4-(4-ethylphenyl)-3-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D292-0266

Molecular Formula

C22H20N4OS (C22 H20 N4 OS)

Compound Name

1-(1,3-benzothiazol-2-yl)-4-(4-ethylphenyl)-3-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

IUPAC name

1-(13-benzothiazol-2-yl)-4-(4-ethylphenyl)-3-methyl-1H4H5H6H7H-pyrazolo[34-b]pyridin-6-one

SMILES

CCc1ccc(C(CC(N2)=O)c3c2n(-c2nc(cccc4)c4s2)nc3C)cc1

InChI

InChI=1S/C22H20N4OS/c1-3-14-8-10-15(11-9-14)16-12-19(27)24-21-20(16)13(2)25-26(21)22-23-17-6-4-5-7-18(17)28-22/h4-11,16H,3,12H2,1-2H3,(H,24,27)/t16-/m0/s1

InChI Key

XKNVADKQCCRIDN-INIZCTEOSA-N

MDL Number (MFCD)

MFCD14816904

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.951

Distribution Coefficient, logD

4.949

Water Solubility, LogSw

-4.60

Polar Surface Area

48.627

Acid Dissociation Constant (pKa)

11.21

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.70

D292-0266 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with D292-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D292-0266?
Check Price and Availability of D292-0266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D292-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D292-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D292-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D292-0266 available by request