D319-0476 Screening compound: ethyl 4-methyl-2-(1,2,3-thiadiazole-4-amido)-1,3-thiazole-5-carboxylate

D319-0476 Screening compound: ethyl 4-methyl-2-(1,2,3-thiadiazole-4-amido)-1,3-thiazole-5-carboxylate
D319-0476 Screening compound: ethyl 4-methyl-2-(1,2,3-thiadiazole-4-amido)-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D319-0476
ethyl 4-methyl-2-(1,2,3-thiadiazole-4-amido)-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D319-0476

Molecular Formula

C10H10N4O3S2 (C10 H10 N4 O3 S2)

Compound Name

ethyl 4-methyl-2-(1,2,3-thiadiazole-4-amido)-1,3-thiazole-5-carboxylate

IUPAC name

ethyl 4-methyl-2-(123-thiadiazole-4-amido)-13-thiazole-5-carboxylate

SMILES

CCOC(c1c(C)nc(NC(c2csnn2)=O)s1)=O

InChI

InChI=1S/C10H10N4O3S2/c1-3-17-9(16)7-5(2)11-10(19-7)12-8(15)6-4-18-14-13-6/h4H,3H2,1-2H3,(H,11,12,15)

InChI Key

GUERGUVRKRHHFE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08547334

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

298.35

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.016

Distribution Coefficient, logD

1.393

Water Solubility, LogSw

-2.59

Polar Surface Area

76.312

Acid Dissociation Constant (pKa)

6.89

Base Dissociation Constant (pKb)

-0.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

D319-0476 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

CNS MPO Library (28609 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Nervous system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D319-0476 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D319-0476?
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What is the minimum amount of D319-0476 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D319-0476
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D319-0476
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D319-0476 available by request