D327-0036 Screening compound: 3-{1-[1-(4-chlorophenyl)cyclopropanecarbonyl]piperidin-4-yl}-5-phenyl-2,3-dihydro-1,3,4-oxadiazol-2-one

D327-0036 Screening compound: 3-{1-[1-(4-chlorophenyl)cyclopropanecarbonyl]piperidin-4-yl}-5-phenyl-2,3-dihydro-1,3,4-oxadiazol-2-one
D327-0036 Screening compound: 3-{1-[1-(4-chlorophenyl)cyclopropanecarbonyl]piperidin-4-yl}-5-phenyl-2,3-dihydro-1,3,4-oxadiazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D327-0036
3-{1-[1-(4-chlorophenyl)cyclopropanecarbonyl]piperidin-4-yl}-5-phenyl-2,3-dihydro-1,3,4-oxadiazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D327-0036

Molecular Formula

C23H22ClN3O3 (C23 H22 ClN3 O3)

Compound Name

3-{1-[1-(4-chlorophenyl)cyclopropanecarbonyl]piperidin-4-yl}-5-phenyl-2,3-dihydro-1,3,4-oxadiazol-2-one

IUPAC name

3-{1-[1-(4-chlorophenyl)cyclopropanecarbonyl]piperidin-4-yl}-5-phenyl-23-dihydro-134-oxadiazol-2-one

SMILES

O=C(C1(CC1)c(cc1)ccc1Cl)N(CC1)CCC1N1N=C(c2ccccc2)OC1=O

InChI

InChI=1S/C23H22ClN3O3/c24-18-8-6-17(7-9-18)23(12-13-23)21(28)26-14-10-19(11-15-26)27-22(29)30-20(25-27)16-4-2-1-3-5-16/h1-9,19H,10-15H2

InChI Key

CREWBZNTQFJRTK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14819232

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.9

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.372

Distribution Coefficient, logD

4.372

Water Solubility, LogSw

-4.88

Polar Surface Area

51.503

Acid Dissociation Constant (pKa)

21.04

Base Dissociation Constant (pKb)

-1.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

D327-0036 in Drug Discovery

Included in Screening Libraries

CNS targets activity set (6557 compounds)

Human GPCR Annotated Library (5539 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Anti-HIV1 Library (19540 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Covalent Inhibitors Library (7986 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • 3D
  • Fragments
Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Ion Channels
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D327-0036 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D327-0036?
Check Price and Availability of D327-0036, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D327-0036 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D327-0036
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D327-0036
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D327-0036 available by request