D341-0254 Screening compound: 4-[4-(3-chlorophenyl)piperazino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

D341-0254 Screening compound: 4-[4-(3-chlorophenyl)piperazino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine
D341-0254 Screening compound: 4-[4-(3-chlorophenyl)piperazino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D341-0254
4-[4-(3-chlorophenyl)piperazino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D341-0254

Molecular Formula

C20H21ClN4S (C20 H21 ClN4 S)

Compound Name

4-[4-(3-chlorophenyl)piperazino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

IUPAC name

3-[4-(3-chlorophenyl)piperazin-1-yl]-8-thia-46-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)35-tetraene

SMILES

Clc1cc(N(CC2)CCN2c2ncnc3c2c(CCCC2)c2s3)ccc1

InChI

InChI=1S/C20H21ClN4S/c21-14-4-3-5-15(12-14)24-8-10-25(11-9-24)19-18-16-6-1-2-7-17(16)26-20(18)23-13-22-19/h3-5,12-13H,1-2,6-11H2

InChI Key

OBJAJBWYMHDXTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04519285

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.93

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.588

Distribution Coefficient, logD

5.576

Water Solubility, LogSw

-6.10

Polar Surface Area

27.719

Acid Dissociation Constant (pKa)

22.15

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

D341-0254 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D341-0254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D341-0254?
Check Price and Availability of D341-0254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D341-0254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D341-0254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D341-0254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D341-0254 available by request