D351-0973 Screening compound: 2-(2-{4-[(2-chlorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)-1-(4-methylpiperidin-1-yl)ethan-1-one

D351-0973 Screening compound: 2-(2-{4-[(2-chlorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)-1-(4-methylpiperidin-1-yl)ethan-1-one
D351-0973 Screening compound: 2-(2-{4-[(2-chlorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)-1-(4-methylpiperidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D351-0973
2-(2-{4-[(2-chlorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)-1-(4-methylpiperidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D351-0973

Molecular Formula

C23H27ClN4OS (C23 H27 ClN4 OS)

Compound Name

2-(2-{4-[(2-chlorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)-1-(4-methylpiperidin-1-yl)ethan-1-one

IUPAC name

2-(2-{4-[(2-chlorophenyl)methyl]-35-dimethyl-1H-pyrazol-1-yl}-13-thiazol-4-yl)-1-(4-methylpiperidin-1-yl)ethan-1-one

SMILES

CC(CC1)CCN1C(Cc1csc(-n2nc(C)c(Cc(cccc3)c3Cl)c2C)n1)=O

InChI

InChI=1S/C23H27ClN4OS/c1-15-8-10-27(11-9-15)22(29)13-19-14-30-23(25-19)28-17(3)20(16(2)26-28)12-18-6-4-5-7-21(18)24/h4-7,14-15H,8-13H2,1-3H3

InChI Key

OCOZAUDCKNNJAH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14822262

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.01

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.266

Distribution Coefficient, logD

5.266

Water Solubility, LogSw

-5.69

Polar Surface Area

40.821

Acid Dissociation Constant (pKa)

20.44

Base Dissociation Constant (pKb)

3.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

D351-0973 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

GPCR Targeted Library (31838 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D351-0973 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D351-0973?
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What is the minimum amount of D351-0973 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D351-0973
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D351-0973
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D351-0973 available by request