D358-0116 Screening compound: 6-(4-ethylpiperazine-1-carbonyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

D358-0116 Screening compound: 6-(4-ethylpiperazine-1-carbonyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
D358-0116 Screening compound: 6-(4-ethylpiperazine-1-carbonyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D358-0116
6-(4-ethylpiperazine-1-carbonyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D358-0116

Molecular Formula

C13H16N4O2S (C13 H16 N4 O2 S)

Compound Name

6-(4-ethylpiperazine-1-carbonyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

IUPAC name

6-(4-ethylpiperazine-1-carbonyl)-5H-[13]thiazolo[32-a]pyrimidin-5-one

SMILES

CCN(CC1)CCN1C(C1=CN=C2SC=CN2C1=O)=O

InChI

InChI=1S/C13H16N4O2S/c1-2-15-3-5-16(6-4-15)11(18)10-9-14-13-17(12(10)19)7-8-20-13/h7-9H,2-6H2,1H3

InChI Key

OIWKQMICXBXPAZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09777270

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

292.36

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

-0.498

Distribution Coefficient, logD

-0.721

Water Solubility, LogSw

-0.87

Polar Surface Area

45.627

Acid Dissociation Constant (pKa)

29.03

Base Dissociation Constant (pKb)

7.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

D358-0116 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

CNS Targets (44014 compounds)

Fragments Library (11262 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Fragments
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D358-0116 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D358-0116?
Check Price and Availability of D358-0116, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D358-0116 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D358-0116
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D358-0116
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D358-0116 available by request