D358-1751 Screening compound: methyl 2-[3-(2-chlorophenyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-amido]-4,5-dimethoxybenzoate

D358-1751 Screening compound: methyl 2-[3-(2-chlorophenyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-amido]-4,5-dimethoxybenzoate
D358-1751 Screening compound: methyl 2-[3-(2-chlorophenyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-amido]-4,5-dimethoxybenzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound D358-1751
methyl 2-[3-(2-chlorophenyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-amido]-4,5-dimethoxybenzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D358-1751

Molecular Formula

C23H18ClN3O6S (C23 H18 ClN3 O6 S)

Compound Name

methyl 2-[3-(2-chlorophenyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-amido]-4,5-dimethoxybenzoate

IUPAC name

methyl 2-[3-(2-chlorophenyl)-5-oxo-5H-[13]thiazolo[32-a]pyrimidine-6-amido]-45-dimethoxybenzoate

SMILES

COC(c(cc(c(OC)c1)OC)c1NC(C1=CN=C2SC=C(c(cccc3)c3Cl)N2C1=O)=O)=O

InChI

InChI=1S/C23H18ClN3O6S/c1-31-18-8-13(22(30)33-3)16(9-19(18)32-2)26-20(28)14-10-25-23-27(21(14)29)17(11-34-23)12-6-4-5-7-15(12)24/h4-11H,1-3H3,(H,26,28)

InChI Key

HUGUEVRSCFYXSZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27581590

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.93

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.172

Distribution Coefficient, logD

-2.195

Water Solubility, LogSw

-3.72

Polar Surface Area

84.073

Acid Dissociation Constant (pKa)

2.03

Base Dissociation Constant (pKb)

-1.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

D358-1751 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with D358-1751 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D358-1751?
Check Price and Availability of D358-1751, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D358-1751 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D358-1751
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D358-1751
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D358-1751 available by request