D376-1239 Screening compound: 2-{2-[(3,4-dimethylphenoxy)methyl]-1,3-thiazol-4-yl}-N-(4-phenyl-1,3-thiazol-2-yl)acetamide

D376-1239 Screening compound: 2-{2-[(3,4-dimethylphenoxy)methyl]-1,3-thiazol-4-yl}-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
D376-1239 Screening compound: 2-{2-[(3,4-dimethylphenoxy)methyl]-1,3-thiazol-4-yl}-N-(4-phenyl-1,3-thiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D376-1239
2-{2-[(3,4-dimethylphenoxy)methyl]-1,3-thiazol-4-yl}-N-(4-phenyl-1,3-thiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D376-1239

Molecular Formula

C23H21N3O2S2 (C23 H21 N3 O2 S2)

Compound Name

2-{2-[(3,4-dimethylphenoxy)methyl]-1,3-thiazol-4-yl}-N-(4-phenyl-1,3-thiazol-2-yl)acetamide

IUPAC name

2-{2-[(34-dimethylphenoxy)methyl]-13-thiazol-4-yl}-N-(4-phenyl-13-thiazol-2-yl)acetamide

SMILES

Cc(cc1)c(C)cc1OCc1nc(CC(Nc2nc(-c3ccccc3)cs2)=O)cs1

InChI

InChI=1S/C23H21N3O2S2/c1-15-8-9-19(10-16(15)2)28-12-22-24-18(13-29-22)11-21(27)26-23-25-20(14-30-23)17-6-4-3-5-7-17/h3-10,13-14H,11-12H2,1-2H3,(H,25,26,27)

InChI Key

UUQHMZXUMHCCEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14825694

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.402

Distribution Coefficient, logD

6.402

Water Solubility, LogSw

-5.62

Polar Surface Area

51.115

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

-0.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

D376-1239 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D376-1239 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D376-1239?
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What is the minimum amount of D376-1239 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D376-1239
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D376-1239
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D376-1239 available by request