D381-0433 Screening compound: 2-(2-chlorophenoxy)-N-(2-methylquinolin-8-yl)propanamide

D381-0433 Screening compound: 2-(2-chlorophenoxy)-N-(2-methylquinolin-8-yl)propanamide
D381-0433 Screening compound: 2-(2-chlorophenoxy)-N-(2-methylquinolin-8-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D381-0433
2-(2-chlorophenoxy)-N-(2-methylquinolin-8-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D381-0433

Molecular Formula

C19H17ClN2O2 (C19 H17 ClN2 O2)

Compound Name

2-(2-chlorophenoxy)-N-(2-methylquinolin-8-yl)propanamide

IUPAC name

2-(2-chlorophenoxy)-N-(2-methylquinolin-8-yl)propanamide

SMILES

CC(C(Nc1cccc2ccc(C)nc12)=O)Oc(cccc1)c1Cl

InChI

InChI=1S/C19H17ClN2O2/c1-12-10-11-14-6-5-8-16(18(14)21-12)22-19(23)13(2)24-17-9-4-3-7-15(17)20/h3-11,13H,1-2H3,(H,22,23)/t13-/m0/s1

InChI Key

HOYCRRYNCAZOSO-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD12915956

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.81

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.820

Distribution Coefficient, logD

4.818

Water Solubility, LogSw

-5.02

Polar Surface Area

38.415

Acid Dissociation Constant (pKa)

11.02

Base Dissociation Constant (pKb)

5.08

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.80

D381-0433 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D381-0433 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D381-0433?
Check Price and Availability of D381-0433, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D381-0433 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D381-0433
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D381-0433
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D381-0433 available by request