D393-0385 Screening compound: 1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-ethylpiperazine

D393-0385 Screening compound: 1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-ethylpiperazine
D393-0385 Screening compound: 1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-ethylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound D393-0385
1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-ethylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D393-0385

Molecular Formula

C20H21ClF3N5 (C20 H21 ClF3 N5)

Compound Name

1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-ethylpiperazine

IUPAC name

1-[3-(2-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[15-a]pyrimidin-7-yl]-4-ethylpiperazine

SMILES

CCN(CC1)CCN1c(n1nc2C(F)(F)F)cc(C)nc1c2-c(cccc1)c1Cl

InChI

InChI=1S/C20H21ClF3N5/c1-3-27-8-10-28(11-9-27)16-12-13(2)25-19-17(14-6-4-5-7-15(14)21)18(20(22,23)24)26-29(16)19/h4-7,12H,3,8-11H2,1-2H3

InChI Key

NSPTWKBXMPFFNU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10478862

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.87

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.401

Distribution Coefficient, logD

3.659

Water Solubility, LogSw

-4.88

Polar Surface Area

26.587

Acid Dissociation Constant (pKa)

25.75

Base Dissociation Constant (pKb)

8.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

D393-0385 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with D393-0385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D393-0385?
Check Price and Availability of D393-0385, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D393-0385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D393-0385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D393-0385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D393-0385 available by request