D430-0126 Screening compound: 4-[4-(4-tert-butylbenzoyl)piperazin-1-yl]-2-methyl-6-(piperidin-1-yl)pyrimidine

D430-0126 Screening compound: 4-[4-(4-tert-butylbenzoyl)piperazin-1-yl]-2-methyl-6-(piperidin-1-yl)pyrimidine
D430-0126 Screening compound: 4-[4-(4-tert-butylbenzoyl)piperazin-1-yl]-2-methyl-6-(piperidin-1-yl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D430-0126
4-[4-(4-tert-butylbenzoyl)piperazin-1-yl]-2-methyl-6-(piperidin-1-yl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D430-0126

Molecular Formula

C25H35N5O (C25 H35 N5 O)

Compound Name

4-[4-(4-tert-butylbenzoyl)piperazin-1-yl]-2-methyl-6-(piperidin-1-yl)pyrimidine

IUPAC name

4-[4-(4-tert-butylbenzoyl)piperazin-1-yl]-2-methyl-6-(piperidin-1-yl)pyrimidine

SMILES

CC(C)(C)c(cc1)ccc1C(N(CC1)CCN1c1nc(C)nc(N2CCCCC2)c1)=O

InChI

InChI=1S/C25H35N5O/c1-19-26-22(28-12-6-5-7-13-28)18-23(27-19)29-14-16-30(17-15-29)24(31)20-8-10-21(11-9-20)25(2,3)4/h8-11,18H,5-7,12-17H2,1-4H3

InChI Key

RHPINQXYWMZSIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18487677

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.600

Distribution Coefficient, logD

5.574

Water Solubility, LogSw

-5.31

Polar Surface Area

40.711

Acid Dissociation Constant (pKa)

22.72

Base Dissociation Constant (pKb)

6.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

D430-0126 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Autophagy-Targeted Library (4564 compounds)

CNS BBB Library (22607 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D430-0126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D430-0126?
Check Price and Availability of D430-0126, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D430-0126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D430-0126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D430-0126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D430-0126 available by request