D430-0218 Screening compound: 1-(4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazin-1-yl)propan-1-one

D430-0218 Screening compound: 1-(4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazin-1-yl)propan-1-one
D430-0218 Screening compound: 1-(4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazin-1-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D430-0218
1-(4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazin-1-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D430-0218

Molecular Formula

C19H25N5O (C19 H25 N5 O)

Compound Name

1-(4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazin-1-yl)propan-1-one

IUPAC name

1-(4-{2-methyl-6-[(4-methylphenyl)amino]pyrimidin-4-yl}piperazin-1-yl)propan-1-one

SMILES

CCC(N(CC1)CCN1c1nc(C)nc(Nc2ccc(C)cc2)c1)=O

InChI

InChI=1S/C19H25N5O/c1-4-19(25)24-11-9-23(10-12-24)18-13-17(20-15(3)21-18)22-16-7-5-14(2)6-8-16/h5-8,13H,4,9-12H2,1-3H3,(H,20,21,22)

InChI Key

MUUHHZAXCGXNRR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19028699

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.640

Distribution Coefficient, logD

3.124

Water Solubility, LogSw

-3.59

Polar Surface Area

47.018

Acid Dissociation Constant (pKa)

17.76

Base Dissociation Constant (pKb)

7.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

D430-0218 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Antifungal Library (16415 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D430-0218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D430-0218?
Check Price and Availability of D430-0218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D430-0218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D430-0218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D430-0218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D430-0218 available by request