D430-0270 Screening compound: N-(4-{[6-(dimethylamino)-2-methylpyrimidin-4-yl]amino}phenyl)propanamide

D430-0270 Screening compound: N-(4-{[6-(dimethylamino)-2-methylpyrimidin-4-yl]amino}phenyl)propanamide
D430-0270 Screening compound: N-(4-{[6-(dimethylamino)-2-methylpyrimidin-4-yl]amino}phenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D430-0270
N-(4-{[6-(dimethylamino)-2-methylpyrimidin-4-yl]amino}phenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D430-0270

Molecular Formula

C16H21N5O (C16 H21 N5 O)

Compound Name

N-(4-{[6-(dimethylamino)-2-methylpyrimidin-4-yl]amino}phenyl)propanamide

IUPAC name

N-(4-{[6-(dimethylamino)-2-methylpyrimidin-4-yl]amino}phenyl)propanamide

SMILES

CCC(Nc(cc1)ccc1Nc1nc(C)nc(N(C)C)c1)=O

InChI

InChI=1S/C16H21N5O/c1-5-16(22)20-13-8-6-12(7-9-13)19-14-10-15(21(3)4)18-11(2)17-14/h6-10H,5H2,1-4H3,(H,20,22)(H,17,18,19)

InChI Key

KPVAZYDIGITEDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD19027164

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

299.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.827

Distribution Coefficient, logD

1.570

Water Solubility, LogSw

-3.23

Polar Surface Area

53.320

Acid Dissociation Constant (pKa)

12.82

Base Dissociation Constant (pKb)

8.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

D430-0270 in Drug Discovery

Included in Screening Libraries

Fragments Library (11262 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D430-0270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D430-0270?
Check Price and Availability of D430-0270, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D430-0270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D430-0270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D430-0270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D430-0270 available by request