D432-0360 Screening compound: 3-(3-methoxyphenyl)-2-{[2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3,4-dihydroquinazolin-4-one

D432-0360 Screening compound: 3-(3-methoxyphenyl)-2-{[2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3,4-dihydroquinazolin-4-one
D432-0360 Screening compound: 3-(3-methoxyphenyl)-2-{[2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D432-0360
3-(3-methoxyphenyl)-2-{[2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D432-0360

Molecular Formula

C27H25N3O3 (C27 H25 N3 O3)

Compound Name

3-(3-methoxyphenyl)-2-{[2-oxo-1-(propan-2-yl)-2,3-dihydro-1H-indol-3-yl]methyl}-3,4-dihydroquinazolin-4-one

IUPAC name

3-(3-methoxyphenyl)-2-{[2-oxo-1-(propan-2-yl)-23-dihydro-1H-indol-3-yl]methyl}-34-dihydroquinazolin-4-one

SMILES

CC(C)N(C(C1CC(N2c3cc(OC)ccc3)=Nc(cccc3)c3C2=O)=O)c2c1cccc2

InChI

InChI=1S/C27H25N3O3/c1-17(2)29-24-14-7-5-11-20(24)22(27(29)32)16-25-28-23-13-6-4-12-21(23)26(31)30(25)18-9-8-10-19(15-18)33-3/h4-15,17,22H,16H2,1-3H3/t22-/m0/s1

InChI Key

CXGLOKHZPJFHEU-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27585666

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.700

Distribution Coefficient, logD

3.690

Water Solubility, LogSw

-4.20

Polar Surface Area

47.599

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

D432-0360 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D432-0360 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D432-0360?
Check Price and Availability of D432-0360, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D432-0360 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D432-0360
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D432-0360
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D432-0360 available by request