D463-0307 Screening compound: 1-[5-methyl-3-(4-methylphenyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-(2-methylprop-2-en-1-yl)piperazine

D463-0307 Screening compound: 1-[5-methyl-3-(4-methylphenyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-(2-methylprop-2-en-1-yl)piperazine
D463-0307 Screening compound: 1-[5-methyl-3-(4-methylphenyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-(2-methylprop-2-en-1-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound D463-0307
1-[5-methyl-3-(4-methylphenyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-(2-methylprop-2-en-1-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D463-0307

Molecular Formula

C23H26F3N5 (C23 H26 F3 N5)

Compound Name

1-[5-methyl-3-(4-methylphenyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-(2-methylprop-2-en-1-yl)piperazine

IUPAC name

1-[5-methyl-3-(4-methylphenyl)-2-(trifluoromethyl)pyrazolo[15-a]pyrimidin-7-yl]-4-(2-methylprop-2-en-1-yl)piperazine

SMILES

CC(CN(CC1)CCN1c(n1nc2C(F)(F)F)cc(C)nc1c2-c1ccc(C)cc1)=C

InChI

InChI=1S/C23H26F3N5/c1-15(2)14-29-9-11-30(12-10-29)19-13-17(4)27-22-20(18-7-5-16(3)6-8-18)21(23(24,25)26)28-31(19)22/h5-8,13H,1,9-12,14H2,2-4H3

InChI Key

CWNJDSRODUVWCH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14830125

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.49

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.306

Distribution Coefficient, logD

5.206

Water Solubility, LogSw

-5.53

Polar Surface Area

26.862

Acid Dissociation Constant (pKa)

25.44

Base Dissociation Constant (pKb)

6.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

D463-0307 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with D463-0307 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D463-0307?
Check Price and Availability of D463-0307, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D463-0307 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D463-0307
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D463-0307
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D463-0307 available by request