D464-0290 Screening compound: N-[(furan-2-yl)methyl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetamide

D464-0290 Screening compound: N-[(furan-2-yl)methyl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetamide
D464-0290 Screening compound: N-[(furan-2-yl)methyl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D464-0290
N-[(furan-2-yl)methyl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D464-0290

Molecular Formula

C14H12N2O2S2 (C14 H12 N2 O2 S2)

Compound Name

N-[(furan-2-yl)methyl]-2-[4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetamide

IUPAC name

N-[(furan-2-yl)methyl]-2-[4-(thiophen-2-yl)-13-thiazol-5-yl]acetamide

SMILES

O=C(Cc1c(-c2cccs2)ncs1)NCc1ccco1

InChI

InChI=1S/C14H12N2O2S2/c17-13(15-8-10-3-1-5-18-10)7-12-14(16-9-20-12)11-4-2-6-19-11/h1-6,9H,7-8H2,(H,15,17)

InChI Key

LBPUWYWHMQOOTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10088602

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

304.39

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.156

Distribution Coefficient, logD

3.156

Water Solubility, LogSw

-3.21

Polar Surface Area

43.332

Acid Dissociation Constant (pKa)

12.87

Base Dissociation Constant (pKb)

1.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

D464-0290 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D464-0290 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D464-0290?
Check Price and Availability of D464-0290, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D464-0290 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D464-0290
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D464-0290
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D464-0290 available by request