D468-1638 Screening compound: 5-bromo-N-(8-butoxyquinolin-5-yl)furan-2-carboxamide

D468-1638 Screening compound: 5-bromo-N-(8-butoxyquinolin-5-yl)furan-2-carboxamide
D468-1638 Screening compound: 5-bromo-N-(8-butoxyquinolin-5-yl)furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D468-1638
5-bromo-N-(8-butoxyquinolin-5-yl)furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D468-1638

Molecular Formula

C18H17BrN2O3 (C18 H17 BrN2 O3)

Compound Name

5-bromo-N-(8-butoxyquinolin-5-yl)furan-2-carboxamide

IUPAC name

5-bromo-N-(8-butoxyquinolin-5-yl)furan-2-carboxamide

SMILES

CCCCOc(c1ncccc11)ccc1NC(c(o1)ccc1Br)=O

InChI

InChI=1S/C18H17BrN2O3/c1-2-3-11-23-14-7-6-13(12-5-4-10-20-17(12)14)21-18(22)15-8-9-16(19)24-15/h4-10H,2-3,11H2,1H3,(H,21,22)

InChI Key

ZNGIGLAFLXIDFW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14830480

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.25

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.534

Distribution Coefficient, logD

4.517

Water Solubility, LogSw

-4.18

Polar Surface Area

48.595

Acid Dissociation Constant (pKa)

8.84

Base Dissociation Constant (pKb)

4.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

D468-1638 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D468-1638 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D468-1638?
Check Price and Availability of D468-1638, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D468-1638 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D468-1638
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D468-1638
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D468-1638 available by request